Allotype Nsi-marker of blood serum beta-globulins in sheep

IN VITRO STUDIES ON ALLOTYPE SUPPRESSION III. Components of Antiallotype Serum Active in Release from Allotype

In rabbits which are heterogeneous with respect to antigenic determinants on serum immunoglobulins (Ig), prenatal or neonatal exposure to antibodies specific for one allelic allotype leads to a long-lasting suppression of that type with compensatory production of the alternate allelic product. This phenomenon, called allotype suppression, was first described by Dray in 1962 (1) . Although many ...

the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation

in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.

Serum immune globulins in Sjögren's syndrome.

Sj6gren's syndrome, a disease principally affecting exocrine glands but with systemic manifestations, is characterized by hypergammaglobulinaemia and the presence of a wide variety of autoantibodies. These are of several types, both organ and non-organ specific, complement-fixing, and precipitating antibodies, and in general are found in a higher proportion of patients than, for instance, in sy...

The Alleged Transformation of Serum Albumin into Serum Globulins.

Action of papain on human serum globulins.

Studies on the degradation of animal and human serum antibody type proteins by various proteolytic enzymes have indicated that molecules of approximately one-half and one-quarter the size of the parent 160,000-molecular weight protein may be readily formed (l-5). Porter (6) has recently shown that rabbit y-globulin is degraded by papain into fragments of the above size range and has separated s...